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KMID : 1143920210250040566
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Annals of Hepato-Biliary-Pancreatic Surgery
2021 Volume.25 No. 4 p.566 ~ p.570
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Gallbladder paraganglioma with hemorrhage: A case report and literature review
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Song Sang-Hwa
Cho Chol-Kyoon
Park Eun-Kyu
Kim Hee-Joon
Hur Young-Hoe
Koh Yang-Seok
Lee Yun-Ho
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Abstract
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Gallbladder paraganglioma (GP) is a rare tumor, with only 12 cases reported in the literature to date. Due to its rarity, clinical information of GP is insufficient. We present a case of GP in a 48-year-old female along with a literature review of all GP cases described to date. A 48-year-old female presented with intermittent right upper abdominal pain. Preoperative imaging revealed a hematoma in the gallbladder lumen without any definite etiology. Laparoscopic cholecystectomy was performed. Gross examination of the gallbladder revealed multiple small stones and a large hematoma as well as a 1.6-cm-sized polypoid mass at the gallbladder fundus. Microscopic study of the polypoid mass showed a zellballen appearance. Immunohistochemical analysis revealed that the mass was positive for synaptophysin, CD56, and chromogranin, suggesting GP. GP is difficult to diagnose because of non-specific clinical findings. Almost all GP cases are diagnosed based on histologic findings after cholecystectomy. Simple cholecystectomy was performed as a treatment in all reported cases of GP, including our case. There was no postoperative tumor recurrence or metastasis after surgery.
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KEYWORD
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Gallbladder, Paraganglioma, Cholecystitis, Hemorrhage, Cholecystectomy
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